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Isodrin

Isodrin is a discontinued insecticide.

Chemical Formula: C₁₂H₈Cl₆

Other names: 1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-endo-1,4-endo-5,8-dimethano-naphthalene

Layman's explanation: Isodrin is a banned and discontinued organochlorine pesticide; structurally it is closely related to aldrin. In the past, it was used as insecticide. It is unstable and may react with light or acids. Isodrin can undergo very slow microbial transformation to endrin. Isodrin is persistent in the environment and sorbs strongly to suspended solids and sediments. It is accumulates in the fatty tissue of the body and biomagnifies particularly in aquatic organisms. Isodrin has not been classified according to its carcinogenicity by EPA yet. However, similar insecticides (e.g., dieldrin) are known to be endocrine disrupters and cause birth defects and cancer. Many organochlorine pesticides have been identified as endocrine disrupters and recent studies focused on their effect on marine life and showed that organochlorine pesticides are significant factors in causing pathological changes and reproductive failures as well as immunity suppression and changes in the development stability in many marine mammals.

Keywords: insecticide, endocrine disrupter

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